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Interactive Papers
A Request From the Media Team:
If you use any of the animations on this website in your class, we would very much appreciate it if you took a few minutes to fill out this survey. Not only will this information will allow us to improve our work, we are a grant funded center and any indication that our work is useful to educators will allow us to continue providing this service to you! We know it's tough to remember to return to this website to fill out a survey, but we would really, really, really appreciate it!
Thank you in advance!
-The LSLC Media Team
Viewing Information:
All of these movies require Macromedia Flash Player for viewing. Click Here to download the plug-in.
Viewing (online): View movies by clicking on its image.
Downloading (for viewing offline): Downloads are in self-extracting zipped folders, the movies can be viewed by opening the HTML file in the unzipped folder after it is extracted.
Note: PC users will have to double-click on the .exe file to begin the extraction, Macs perform this function automatically.
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 | AIDS, HIV and tRNA
Adapted from a research paper published in 2001, written by Matthew Renda and others, this interactive paper describes an experiment that tests whether an altered tRNA can be used to stop Human Immunodeficiency Virus (HIV) from converting its single-stranded RNA into double-stranded DNA. This conversion is a necessary step for HIV to infect human cells.
| Addresses the following biological concepts: Amino Acids, Complementarity of DNA and/or RNA, DNA replication, Enyzmes,Flow Cytometry, HIV, Independent vs Dependent variables, Inquiry/Experimental design, Nucleotides, Polymerases, Ribosomes, The immune system, Translation, Viruses.
(Run time = ~ 1.5 hours, 555 KB)
Download Flash Movie (PC)
Download Flash Movie (Mac)
Teacher's guide to the interactive paper (including paper outline)
Color key for nucleotides in the interactive paper
Sample assessment questions and learning objectives for each section
Connections to New York State Living Environment Core Curriculum
Powerpoint on AIDS Vaccine Research (by Ramil Sapinoro)
Pubmed link to Renda, et. al., 2001
Link to the Dewhurst Laboratory at the University of Rochester Medical Center
Laboratory Activity: Studying Viruses
Laboratory Activity: Competitive Inhibition
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 | Bacterial Homeostasis and Tooth Decay
Adapted from a research paper published in 2004, written by Wendi Kuhnert and others, this research paper describes an experiment that addresses how a bacteria that causes tooth decay can survive at low pH.
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Addresses the following biological concepts: Active transport, Anaerobic respiration, ATP, Biofilms, Cell membranes, Complementarity of DNA and/or RNA, Diffusion (concentration gradients), Enzymes, Homeostasis, How organisms use DNA to create proteins, Independent vs Dependent variables, Inquiry/Experimental design, pH, Protein channels, Transcription, Translation.
(Run time = ~ 1.5 hours, 371 KB)
Download Flash Movie (PC)
Download Flash Movie (Mac)
Teacher's guide to the interactive paper (including paper outline)
Sample assessment questions and learning objectives for each section
Connections to New York State Living Environment Core Curriculum
Additional Information about S. Mutans and Experimental Therapies
Pubmed link to Kuhnert, et. al., 2004
Link to the Quivey Laboratory at the University of Rochester Medical Center
Laboratory Activity: Critiquing a Science Fair Experiment
Laboratory Activity: Transformation, The Case of the Necessary Gene
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Questions?
If you have questions about any of the content or techniques described in these papers, please email LSLC_Media@urmc.rochester.edu and we will find the answers! We encourage you to have your students examine the experiments with a critical eye. If they feel that they have an alternative hypothesis that is supported by the data, we would be happy to start a dialog with scientists in the field.
This project was funded by the Waksman Foundation for Microbiology
See the Waksman Foundation website for information about grants and other resources for K-12 teachers
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